ABSTRACT
<i></i>Background: Diabetes mellitus is a chronic hyperglycaemic syndrome prevalent worldwide which predisposes to increased cardiovascular mortality and morbidity. Dyslipidaemia significantly contributes to the increased risk of cardiovascular disease and other morbidities in these subjects. Several studies conducted in the past shows that the non-pharmacological approach such as lifestyle modification that is yoga practices on daily basis have resulted in improvement in dyslipidemia status in cardiovascular disease. Aim and Objectives: This study was conducted to study the effect of Yogic Asanas on lipid profile in type 2 diabetic subjects. Materials and Methods: This is a prospective randomized control study. We enrolled 80 Type 2 diabetic subjects both males and females in the age group of 40–60 years based on inclusion and exclusion criteria from January 2021 to September 2021. Before and after 3 months of yoga and pranayama repeat fasting blood samples were taken from all the participants for lipid profile parameters estimation. All the results obtained before and after yoga and pranayama were compared using Statistical Package for the Social Sciences version 20, student paired t test. A P < 0.05 was considered statistically significant. Results: Yogic exercises significantly benefits the diabetes patients with their lipid profile levels. Conclusion: Yogic exercises would give benefit to the patient by reducing cholesterol and low- density lipoprotein cholesterol levels as well as increasing high-density lipoprotein levels and improve the status of patients in terms of use of less medicine, improvement of physical well-being leading to complication-free life.
ABSTRACT
Background: Total white blood cell (WBC) count is an effective marker of chronic inflammation. Granulocyte, specifically eosinophil play significant role in endothelial dysfunction, vasoconstriction, inflammation, and thrombosis. Along with eosinophil, previous studies reported increased activity of monocytes in hypertension (HT). Nowadays, in a medical research, we are using mathematical calculations, which is more accurate in this study. Aim and Objectives: This study was conducted to find out association of total WBC count and eosinophil to monocyte ratio (EMR) in hypertensives and normotensives. Materials and Methods: In study group, 50 hypertensives aged 40–60 years, males and females with the history of previously diagnosed HT >1 year duration, or taking antihypertensive medications with blood pressure (BP) Systolic BP (SBP) >140 mm Hg, Diastolic BP >90 mmHg were taken. In control group, 50 normotensives aged 40–60, males and females with SBP <140 mmHg, DBP <90 mmHg were taken, who were matching socioeconomically with study group. BP was measured, and venous blood samples were collected with proper aseptic precautions. Results: Study shows significantly (P < 0.05) high total WBC count, Eosinophil count and Monocyte count in hypertensives. EMR is also high but it is statistically not significant. Conclusion: High total WBC count, eosinophil count and monocyte count predicts risk of adverse cardiovascular events but change in EMR is not associated with HT.